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If cessation of therapy is indicated, it may be appropriate to taper the methadone dose, rather than abruptly discontinue it, due to the risk of precipitating withdrawal symptoms. Ask yourself if you know the locations of any of these facilities. LIFE-THREATENING RESPIRATORY DEPRESSION: Serious, life-threatening, or fatal respiratory depression may occur. Many opioid addicts suffer from poor health conditions, have dysfunctional relations in their families, are homeless, unemployed, and engage in unhealthy, immoral, or unsafe activities that make them less likely to refrain from illicit opioid use without extensive help. 07(c)), to facilitate the treatment of the primary admitting diagnosis. Interactions With Other CNS Depressants Patients receiving other opioid analgesics, general anesthetics, phenothiazines or other tranquilizers, sedatives, hypnotics, or other CNS depressants (including alcohol) concomitantly with methadone may experience respiratory depression, hypotension, profound sedation, or coma (see PRECAUTIONS).

Patients should be cautioned that alcohol and other CNS depressants may produce an additive CNS depression when taken with this product and should be avoided. Oral: Day 1: Administer initial dose under supervision when symptoms of withdrawal are present. -Initial dose: 20 to 30 mg orally; an additional 5 to 10 mg may be given orally after 2 to 4 hours if withdrawal symptoms have not been suppressed or if symptoms reappear. -Maximum initial dose: 30 mg -Maximum day 1 dose: 40 mg -Adjust dose over the first week based on control of withdrawal symptoms at 2 to 4 hours after dosing; titrate carefully as methadone levels will accumulate over the first several days of dosing. Due to its activity at the NMDA receptor, it may be more effective against neuropathic pain; for the same reason, tolerance to the analgesic effects may be less than that of other opioids.[18][19] People with long-term pain will sometimes have to perform so-called opioid rotation.[20] Opioid rotation involves switching from one opioid to another, usually at intervals of between a few weeks, or more commonly, several months. A 2009 Cochrane review found methadone was effective in retaining people in treatment and in the reduction or cessation of heroin use as measured by self-report and urine/hair analysis but did not affect criminal activity or risk of death.[15] The treatment of opioid-dependent persons with methadone will follow one of two routes.[citation needed] Methadone maintenance therapy (MMT) usually takes place as an outpatient.

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Subutex® has only buprenorphine as an active ingredient. Most have been 10 mg. but I think they still make the 40 mg. as well as the 5 mg. Consumers swallow the liquid drug in front of a pharmacist daily.

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Read More I went to a clinic in Detroit to get started and my first visit was only about 20 min with the doc---Although before that I had to fill out about 20 pages of paperwork but nothing to grueling and my insurance covers it so you might want to look into it---But I don't think you will find somewhere that you can just walk into and walk out of with a script--- Read More I live in DC where I don't believe treatments with bupopherine or whatever is legal. A 2004 GAO study notes that placement of clinics can impede recovery and exacerbate relapse: “Although these clinics are intended to help those in need of rehabilitation, patients who seek treatment must navigate their way to and from the clinics in an environment in which illegal sales of narcotics are daily occurrences. Gennadiy Onishchenko, Chief Sanitary Inspector, claimed in 2008 that health officials are not convinced of the treatment's efficacy.

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These methadone clinics and centers provide ease of access to the necessary prescription methadone that will ease withdrawals, reduce or eliminate cravings and help patients to live a more satisfying and healthy lifestyle. The changes were expected to improve the quality of care provided in an OTP with increased professional discretion and individualized treatment plans, increasing the focus on performance outcomes, and expanding the availability of opioid addiction treatments to more individuals who would benefit from the life saving services they offer. Read More however I did get a bit more of a realistic mental clarity while on suboxone that I didnt get from methadone. 1 doctor agreed: INTERNET: Look it up on SUBOXONE. Read More An example of this would be switching from oxycontin to methadone for a few months, or from methadone to mscontin, etc. The changes were expected to improve the quality of care provided in an OTP with increased professional discretion and individualized treatment plans, increasing the focus on performance outcomes, and expanding the availability of opioid addiction treatments to more individuals who would benefit from the life saving services they offer.

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