There are numerous factors that influence how a person will respond to varying methadone dosages: the number of years they have been addicted to opioids the type of opioids used and the amount the frequency of use method of use (oral, inhalation, or injection) as well as the person’s general state of health including liver functioning and other factors. Methadone can cause slow or shallow breathing and dangerous changes in heartbeat that may not be felt by the patient." The advisory urged that physicians use caution when prescribing methadone to people who are not used to the drug and that people take the drug exactly as directed.[23] Adverse effects of methadone include:[citation needed] Sedation Diarrhea[24] or constipation[24][25] Flushing[25] Perspiration[25] and sweating[25] Heat intolerance Dizziness[24][26][27] or fainting[24][26][27] Weakness[25] Chronic fatigue, sleepiness[25] and exhaustion Sleep problems such as drowsiness,[24] trouble falling asleep (Insomnia),[25][26] and trouble staying asleep[25] Constricted pupils Dry mouth[24][25] Nausea[24][25] and vomiting[24][25] Low blood pressure Hallucinations[24][26] or confusion[24][26] Headache[25] Heart problems such as chest pain[24][26] or fast/pounding heartbeat[24][26][27] Abnormal heart rhythms[27][28] Respiratory problems such as trouble breathing,[24][26] slow or shallow breathing (hypoventilation),[24][26] light-headedness,[24][26][27] or fainting[24][26] Loss of appetite,[24][25] and in extreme cases anorexia Weight gain[25] Memory loss Stomach pains[25] Itching Difficulty urinating[25] Swelling of the hands, arms, feet, and legs[25] Feeling restless[24] or agitated Mood changes,[25] euphoria, disorientation Nervousness[24] or anxiety[24][26] Blurred vision[25] Decreased libido,[24][25] missed menstrual periods,[25] difficulty in reaching orgasm,[24] or impotence[24][25] Skin rash Seizures Central sleep apnea Withdrawal symptoms[edit] Physical symptoms[citation needed] Lightheadedness[29] Tearing of the eyes[29][30] Mydriasis (dilated pupils)[29] Photophobia (sensitivity to light) Hyperventilation syndrome (breathing that is too fast/deep) Runny nose[30] Yawning Sneezing[30] Nausea,[29][30] vomiting,[29][30] and diarrhea[29] Fever[30] Sweating[29] Chills[30] Tremors[29][30] Akathisia (restlessness) Tachycardia (fast heartbeat)[30] Aches[29] and pains, often in the joints or legs Elevated pain sensitivity Blood pressure that is too high (hypertension, may cause stroke) Cognitive symptoms[citation needed] Suicidal ideation Susceptibility to cravings[29] Depression[29] Spontaneous orgasm Prolonged insomnia Delirium Auditory hallucinations Visual hallucinations Increased perception of odors (olfaction), real or imagined Marked decrease or increase in sex drive Agitation Anxiety[29] Panic disorder Nervousness[29] Paranoia Delusions Apathy Anorexia (symptom) Methadone withdrawal symptoms are reported as being significantly more protracted than withdrawal from opioids with shorter half-lives. Marino was once a respected player in Christchurch's underworld - she started drinking alcohol and dabbling in crime at the age of 10 and by 18 she was a drug dealer.
The private clinics are more expensive to attend but usually have either a short or no waiting list. Long-term use of opioid medication may affect fertility (ability to have children) in men or women. However, if you are thinking about using this narcotic to try to cure your heroin or severe opioid addiction, then you should get help from an addiction specialist, or an addiction treatment center.
Drug Interactions (see DRUG INTERACTIONS) Methadone undergoes hepatic N-demethylation by cytochrome P-450 isoforms, principally CYP3A4, CYP2B6, CYP2C19, and to a lesser extent by CYP2C9 and CYP2D6. Methadone has been detected in amniotic fluid and cord plasma at concentrations proportional to maternal plasma and in newborn urine at lower concentrations than corresponding maternal urine. Everyone reacts/responds differently to medication and to addiction, so your doctor and answer your question to this best. This should be considered when prescribing or dispensing methadone hydrochloride oral concentrate in situations where the clinician is concerned about an increased risk of misuse, abuse, or diversion. Consult your doctor or healthcare if constipation continues or becomes bothersome. Patients who use other substances of abuse should not breastfeed.
However, if you have developed a strong tolerance to opioids by taking heroin, Oxycontin, or other similar drugs for years, then you may need higher doses. What are the symptoms he's experiencing when he says he isn't feeling right? ## never heard of cloudy methadone unless juice is added.even then its not cloudy. In the epidode "Job", Jack and Victor help him get a job. Other side effects include weakness, headache, constipation, itching, and dry mouth.
If side effects, such as weight loss or loss of appetite, become severe or bothersome, talk to your doctor for specific recommendations. More expensive but less strict guidelines to follow. Consult with your healthcare provider if the Methadone is not adequately controlling the pain. Patients who are ambulatory should be cautioned that methadone, like other opioids, may produce orthostatic hypotension. As of 2013 due to the strict changes in receiving prescription pain medication as well as decreases in prescription abuse the requirements to be accepted into methadone clinics have changed in areas such as New York State. Women of childbearing potential who become or are planning to become pregnant should be advised to consult their physicians regarding the effects of methadone use during pregnancy. Continue to smoke indica marijuana (not sativa!), and stopclonidine in about 10 days. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects.
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